Chronic Myelogenous Leukemia is the cancer of the white blood cells. This happens when there is an increased development of myeloid cells in the bone marrow, and the pile of these cells occurs in the blood. The chronic myelogenous leukemia is a chronic cancer on the clonal bone marrow, and it is a stem cell disorder where the accumulation of mature neutrophils, eosinophils, and basophils. They are treated with drugs namely tyrosine-kinase inhibitors which have increased lifespan rates after introducing the drug in 2001. This is considered better than chemotherapy, and the rates increase from 15-25% every year in adult leukemia. Children suffering from chronic myelogenous leukemia are also increasing at a 5% rate per year. Chronic myelogenous leukemia is most common prevalent in males rather than females making the ration 1.4:1 with the males above age 65 diagnosed. One reason for the appearance of chronic myelogenous leukemia is the exposure to radiation, for example, mil workers, scientists, radiotherapists, bombing survivors etc. Such individuals even after treating can live up to another ten years or so. Chronic myelogenous leukemia has three stages based on laboratory research work and clinical characteristics. This starts with a chronic phase where research says around 85% of patients are in this phase at the time of diagnosis. In this stage, patients have mild symptoms like weakness, one-sided pain, joint or hip pain bloatness, etc. The duration of chronic phase depends on when the illness is diagnosed. When the chronic phase is not recognized is the second phase called the acceleration phase. If you are likely to start the medication, then there is a room for improvement. The ignored chronic phase conditions that transitions to accelerated phase could be low platelet count, abnormalities evolving then and there, the presence of 10-20% of myoblasts in the blood or bone marrow. The accelerated phase is where the disease starts showing the prominent features, and it moves into the third phase called blast crisis. Here the drug treatments can show very less effectiveness, and it is acute leukemia with a shorter lifespan. Once the content of myoblasts is more than 20%, this is a serious case to look at. There would be large clusters of blasts in the bone marrow while biopsy tests are done. During the blast crisis, there would be solid proof of leukemia outside the bone marrow as well.